Oncogenic fusion transcript analysis identified ADAP1-NOC4L, potentially associated with metastatic colorectal cancer.

Amin TalebiSoodabeh ShahidsalesMohsen AliakbarianMasoud Pezeshki RadMohammad Amin Kerachian

Published in: Cancer medicine (2022)

ADAP1-NOC4L transcript chimera, a driver chimera identified in this study, provides new insight into the underlying mechanisms involved in the development and spread of mCRC. It suggests the potential of RNA-based alterations as novel targets for personalized medicine in clinical practice.

Keyphrases

metastatic colorectal cancer
clinical practice
rna seq
single cell
risk assessment
human health
nucleic acid
data analysis