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Post-registration experience of nivolumab in advanced hepatocellular carcinoma: an international study.

David J PinatoAhmed KasebYinghong WangAnwaar SaeedDavid SzafronTomi JunSirish DharmapuriAbdul Rafeh NaqashMahvish MuzaffarMusharraf NavaidUqba KhanChiehJu LeeAnushi BulumulleBo YuSonal PaulNeil NimkarDominik BettingerFrancesca BeneventoHannah HildebrandTiziana PressianiYehia I AbugabalNicola PersoneniYi-Hsiang HuangLorenza RimassaCelina AngThomas MarronDavid J Pinato
Published in: Journal for immunotherapy of cancer (2021)
This study confirms safety and efficacy of nivolumab in advanced HCC across various lines of therapy and degrees of liver dysfunction. Despite equal ORR and toxicity to nivolumab, patients with CP-B functional class have shorter survival than the patients with CP-A.
Keyphrases
  • stem cells
  • free survival