A Nomogram for Predicting ADHD and ASD in Child and Adolescent Mental Health Services (CAMHS).
Hilario Blasco-FontecillaChao LiMiguel VizcainoRoberto Fernández-FernándezJuan-Antonio VargasMarcos Bella-FernándezPublished in: Journal of clinical medicine (2024)
Objectives: To enhance the early detection of Attention Deficit/Hyperactivity Disorder (ADHD) and Autism Spectrum Disorder (ASD) by leveraging clinical variables collected at child and adolescent mental health services (CAMHS). Methods: This study included children diagnosed with ADHD and/or ASD ( n = 857). Three logistic regression models were developed to predict the presence of ADHD, its subtypes, and ASD. The analysis began with univariate logistic regression, followed by a multicollinearity diagnostic. A backward logistic regression selection strategy was then employed to retain variables with p < 0.05. Ethical approval was obtained from the local ethics committee. The models' internal validity was evaluated based on their calibration and discriminative abilities. Results: The study produced models that are well-calibrated and validated for predicting ADHD (incorporating variables such as physical activity, history of bone fractures, and admissions to pediatric/psychiatric services) and ASD (including disability, gender, special education needs, and Axis V diagnoses, among others). Conclusions: Clinical variables can play a significant role in enhancing the early identification of ADHD and ASD.
Keyphrases
- attention deficit hyperactivity disorder
- autism spectrum disorder
- mental health
- intellectual disability
- young adults
- physical activity
- healthcare
- working memory
- primary care
- body mass index
- public health
- multiple sclerosis
- machine learning
- bone mineral density
- lymph node metastasis
- depressive symptoms
- deep learning
- bioinformatics analysis