Identifying the Mechanism of Polygoni Cuspidati Rhizoma et Radix in Treating Acute Liver Failure Based on Network Pharmacology and Molecular Docking.

Jing Hong Jie Ding Han-Han Hong Xiao-Wan Xu Bo Pan Yi Ruan Xiao-Feng Zhai

Published in: Gastroenterology research and practice (2022)

This is the first study to explore the therapeutic mechanisms of PCRR in ALF via network pharmacology and molecular docking. This study provides a research platform with candidate ALF-related targets of PRCC for the development of therapeutics against ALF.

Keyphrases

molecular docking
liver failure
molecular dynamics simulations
hepatitis b virus
high throughput
small molecule
intensive care unit