Treatment of severe stable COPD: the multidimensional approach of treatable traits.
Marlies van DijkChristiaan T GanT David KosterPeter J WijkstraDirk-Jan SlebosHuib A M KerstjensHester van der VaartMarieke L DuivermanPublished in: ERJ open research (2020)
Now that additional treatment options for severe chronic obstructive pulmonary disease (COPD) have emerged in recent years, patients with severe COPD should not be left in the rather hopeless situation of "there is nothing to improve" any more. Inertia or fatalism is a disservice to our patients. Ranging from advanced care planning to quite intense and demanding therapies such as multidisciplinary pulmonary rehabilitation, (endoscopic) lung volume reduction, chronic noninvasive ventilation and lung transplantation, caregivers should try to provide a personalised treatment for every severe COPD patient. In this review, we aim to describe the multidimensional approach to these patients at our centre along the lines of treatable traits leading to specific additional treatment modalities on top of standard care.
Keyphrases
- chronic obstructive pulmonary disease
- lung function
- healthcare
- palliative care
- early onset
- end stage renal disease
- quality improvement
- chronic kidney disease
- pulmonary hypertension
- genome wide
- pain management
- gene expression
- intensive care unit
- dna methylation
- mechanical ventilation
- psychometric properties
- acute respiratory distress syndrome