Synergistic effect of vancomycin combined with cefotaxime, imipenem, or meropenem against Staphylococcus aureus with reduced susceptibility to vancomycin

Arpasiri Srisrattakarn Chonthicha Chaiyapoke Sirikarn Booncharoen Sujintana Wongthong Aroonwadee Chanawong Patcharaporn Tippayawat Ratree Tavichakorntrakool Aroonlug Lulitanond

Published in: Turkish journal of medical sciences (2021)

This study demonstrated in vitro enhanced antibacterial activity of vancomycin plus β-lactams against clinical hVISA or VISA isolates. These combinations may be an alternative treatment for MRSA infections in clinical practice.

Keyphrases

methicillin resistant staphylococcus aureus
staphylococcus aureus
clinical practice
biofilm formation
escherichia coli
pseudomonas aeruginosa
multidrug resistant
gram negative
replacement therapy
silver nanoparticles