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Oxidative stress-induced chromosome breaks within the ABL gene: a model for chromosome rearrangement in nasopharyngeal carcinoma.

Sang-Nee TanSai-Peng SimAlan Soo-Beng Khoo
Published in: Human genomics (2018)
Our findings suggested that oxidative stress-induced apoptosis may participate in chromosome rearrangements of NPC. A revised model for oxidative stress-induced apoptosis mediating chromosome rearrangement in NPC is proposed.
Keyphrases
  • induced apoptosis
  • oxidative stress
  • endoplasmic reticulum stress
  • copy number
  • signaling pathway
  • diabetic rats
  • dna damage
  • ischemia reperfusion injury
  • genome wide
  • dna methylation
  • tyrosine kinase