The Synergistic Effect of Piperlongumine and Sanguinarine on the Non-Small Lung Cancer.
Marta Hałas-WiśniewskaWioletta ZielińskaMagdalena IzdebskaAlina GrzankaPublished in: Molecules (Basel, Switzerland) (2020)
Selected alkaloids exhibit a cytotoxic effect on A549 cells. In turn, treatment with the combination of PL and SAN in a 4:1 ratio indicates a synergistic effect and is associated with an increase in the level of reactive oxygen species (ROS).