Generation and validation of novel conditional flox and inducible Cre alleles targeting fibroblast growth factor 18 (Fgf18).

Andrew S HaganMichael BoylanCraig SmithEstela Perez-SantamarinaKarolina KowalskaIrene H HungRenate M LewisMohammad K HajihosseiniMark LewandoskiDavid M Ornitz

Published in: Developmental dynamics : an official publication of the American Association of Anatomists (2019)

These alleles will be useful to investigate FGF18 function during organogenesis and tissue homeostasis, and to target specific cell lineages at embryonic and postnatal time points.

Keyphrases

single cell
preterm infants
cell therapy
stem cells
drug delivery
clinical evaluation