Safety Assessment of Neoadjuvant Pertuzumab Combined with Trastuzumab in Nonmetastatic HER2-Positive Breast Cancer in Postmenopausal Elderly Women of South Asia.
Nadia HussainAmira S A SaidZainab KhanPublished in: International journal of breast cancer (2018)
Comparing neoadjuvant TCP and neoadjuvant TCH-P showed TCH-P regimen had an acceptable toxicity profile. Severe cardiac dysfunction was not observed. Using TCH-P regimen can be considered as relatively safe therapeutic option for elderly postmenopausal women with nonmetastatic HER2-positive breast cancer.
Keyphrases
- positive breast cancer
- rectal cancer
- locally advanced
- lymph node
- breast cancer risk
- epidermal growth factor receptor
- middle aged
- bone mineral density
- oxidative stress
- community dwelling
- metastatic breast cancer
- squamous cell carcinoma
- polycystic ovary syndrome
- left ventricular
- radiation therapy
- type diabetes
- heart failure
- metabolic syndrome
- body composition
- skeletal muscle
- tyrosine kinase
- adipose tissue