Parallel Multi-Omics in High-Risk Subjects for the Identification of Integrated Biomarker Signatures of Type 1 Diabetes.
Oscar AlcazarLuis F HernandezErnesto S NakayasuCarrie D NicoraCharles AnsongMichael J MuehlbauerJames R BainCiara J MyerSanjoy K BhattacharyaPeter BuchwaldMidhat H AbdulredaPublished in: Biomolecules (2021)
Preliminary parallel quadra-omics provided a comprehensive picture of disturbances in high-risk T1D subjects and highlighted the potential for identifying associated integrated biomarker signatures. With further development and validation in larger cohorts, parallel multi-omics could ultimately facilitate the classification of T1D progressors from non-progressors.