An Untargeted Metabolomics Approach on Carfilzomib-Induced Nephrotoxicity.

Ioanna BarlaPanagiotis EfentakisSofia LamprouMaria GavriatopoulouMeletios- Athanasios Dimopoulos Evangelos TerposIoanna AndreadouΝikolaos S Τhomaidis Evangelos Gikas

Published in: Molecules (Basel, Switzerland) (2022)

Cfz causes metabolite retention in kidney and dysregulates (up and down) several metabolites associated with the occurrence of inflammation and oxidative stress.

Keyphrases

oxidative stress
diabetic rats
mass spectrometry
drug induced
high glucose
risk assessment
dna damage
ischemia reperfusion injury
ms ms
multiple myeloma
liquid chromatography
induced apoptosis
high resolution
heat shock
heat shock protein