Identification of aberrant innate and adaptive immunity based on changes in global gene expression in the blood of adults with autism spectrum disorder.

Fumie HoriuchiYuta YoshinoHiroshi KumonRie HosokawaKiwamu NakachiKentaro KawabeJun-Ichi IgaShu-Ichi Ueno

Published in: Journal of neuroinflammation (2021)

The dysregulated gene expressions confirmed in the blood of adults with ASD were relevant to the dysfunction of innate and adaptive immunity. These findings may aid in understanding the pathogenesis of ASD.

Keyphrases

immune response
gene expression
autism spectrum disorder
attention deficit hyperactivity disorder
dna methylation
intellectual disability
genome wide
working memory