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Clinical decision-making and health-related quality of life during first-line and maintenance therapy in patients with advanced non-small cell lung cancer (NSCLC): findings from a real-world setting.

Monika SztankayJohannes Maria GiesingerAugust ZaberniggElisabeth KremplerGeorg PallWolfgang HilbeOtto BurghuberMaximilian HochmairGerhard RumpoldStephan DoeringBernhard Holzner
Published in: BMC cancer (2017)
Our results indicate that HRQOL and symptom burden improve between first-line treatment to MT in some respects, although some late toxicity persists. Discrepancies between patients' and physicians' perception of reasons for rejecting MT were evident. Thus, the integration of patient-reported outcomes, such as HRQOL, is required to enable shared decision-making and personalised healthcare based on mutual understanding of treatment objectives.
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