Immunosuppressive effect of mesenchymal stem cells on lung and gut CD8+ T cells in lipopolysaccharide-induced acute lung injury in mice.

Yanping XuJiaqi ZhuBing FengFeiyan LinJiahang ZhouJingqi LiuXiaowei ShiXuan LuQiaoling PanJiong YuYing ZhangLan-Juan Li Hongcui Cao

Published in: Cell proliferation (2021)

The present research indicates that MSCs attenuate lung and gut injury partly via regulation of the immune response in the lungs and intestines and gut microbiota, providing new insights into the mechanisms underlying the therapeutic effects of MSC treatment for LPS-induced ALI.

Keyphrases

lipopolysaccharide induced
inflammatory response
lps induced
mesenchymal stem cells
immune response
toll like receptor
umbilical cord
bone marrow
high fat diet induced
type diabetes
dendritic cells
cell therapy
metabolic syndrome
adipose tissue
wild type