Elevated White Blood Cell Count Does Not Predict Clostridium difficile Nucleic Acid Testing Results.
Matthew M YehPatrick C MathiasNiklas KrummAndrew BryanFerric C FangAlex L GreningerPublished in: Clinical infectious diseases : an official publication of the Infectious Diseases Society of America (2021)
Although WBC is an important prognostic indicator in patients with CDI, an isolated WBC elevation has low sensitivity and specificity as a predictor of fecal C. difficile NAAT positivity in the inpatient setting. A high or rising WBC in isolation is not a sufficient indication for CDI testing.