CCL2 promotes lymphatic metastasis via activating RhoA and Rac1 pathway and predict prognosis to some extent in tongue cancer.
Yuqing DongShuning ZhangShuangyuan ZhaoMing XuanGuiquan ZhuZhuang ZhangWeihua GuoPublished in: Cancer biology & therapy (2023)
CCL2 promotes the invasion and metastasis of tongue cancer by PI3K/Akt pathway. The plasma level of CCL2 may predict prognosis of tongue cancer patients. CCL2 can serve as a potential therapeutic target for tongue cancer treatment.