Inhibition of SARS-CoV-2 Infection in Human Airway Epithelium with a Xeno-Nucleic Acid Aptamer.
Niayesh RaziWeizhong LiMaxinne A IgnacioJeffrey M LoubeEva L AgostinoXiaoping ZhuMargaret A ScullJeffrey J DeStefanoPublished in: bioRxiv : the preprint server for biology (2023)
Together, these results suggest that FANA-R8-9 effectively prevents infection by specific SARS-CoV-2 variants and indicate that aptamer technology could be utilized to target other clinically-relevant viruses in the respiratory mucosa.