Type 2 Diabetes Remission in Patients with Heterozygous Variants in the Leptin-Melanocortin Pathway after Roux-en-Y Gastric Bypass: A Matched Case-Control Study.

Diego AnazcoWissam GhusnAlejandro CamposLizeth CifuentesSima FansaElif TamaJoshua T BublitzKhushboo GalaMaria D HurtadoJanet E OlsonAndres Acosta

Published in: Obesity surgery (2023)

Despite inferior weight loss outcomes at nadir, carriers had similar T2D remission rates when compared to non-carriers. Weight-independent metabolic benefits of RYGB might contribute to this observation.

Keyphrases

roux en y gastric bypass
weight loss
glycemic control
type diabetes
bariatric surgery
gastric bypass
disease activity
ulcerative colitis
obese patients
copy number
weight gain
rheumatoid arthritis
early onset
systemic lupus erythematosus
cardiovascular disease