Structural and functional polarisation of human pancreatic beta cells in islets from organ donors with and without type 2 diabetes.

Louise Cottle Wan Jun Gan Ian GilroyJaswinder S SamraAnthony J Gill Thomas Loudovaris Helen E Thomas Wayne J Hawthorne Melkam Alamerew KebedePeter Thorn

Published in: Diabetologia (2021)

Structural and functional polarisation is a defining feature of human pancreatic beta cells and plays an important role in the control of insulin secretion.

Keyphrases

induced apoptosis
endothelial cells
type diabetes
cell cycle arrest
induced pluripotent stem cells
machine learning
endoplasmic reticulum stress
oxidative stress
cell death
signaling pathway