Angioblast Derived from ES Cells Construct Blood Vessels and Ameliorate Diabetic Polyneuropathy in Mice.

Tatsuhito HimenoHideki KamiyaKeiko NaruseZhao ChengSachiko ItoTaiga ShibataMasaki KondoJiro KatoTetsuji OkawaAtsushi FujiyaHirohiko SuzukiTetsutaro KitoYoji HamadaYutaka OisoKenichi IsobeJiro Nakamura

Published in: Journal of diabetes research (2015)

These results suggest that transplantation of angioblast like cells induced from embryonic stem cells appears to be a novel therapeutic strategy for diabetic polyneuropathy.

Keyphrases

embryonic stem cells
induced apoptosis
type diabetes
wound healing
cell cycle arrest
high glucose
diabetic rats
endoplasmic reticulum stress
drug induced
oxidative stress
cell therapy
signaling pathway
bone marrow
metabolic syndrome
endothelial cells
adipose tissue
insulin resistance
pi k akt