Vitamin K antagonists with or without long-term antiplatelet therapy in outpatients with stable coronary artery disease and atrial fibrillation: Association with ischemic and bleeding events.
Gilles LemesleGregory DucrocqYedid ElbezEric Van BelleShinya GotoChristopher P CannonChristophe BautersDeepak L BhattPhilippe Gabriel Stegnull nullPublished in: Clinical cardiology (2017)
In this observational analysis, the use of APT in addition to OAC in patients with stable CAD and AF was not associated with lower risk of ischemic events but possibly with higher bleeding rates. Randomized trials are necessary to determine the optimal long-term antithrombotic strategy.
Keyphrases
- atrial fibrillation
- percutaneous coronary intervention
- antiplatelet therapy
- coronary artery disease
- oral anticoagulants
- catheter ablation
- left atrial
- acute coronary syndrome
- left atrial appendage
- direct oral anticoagulants
- coronary artery bypass grafting
- heart failure
- ischemia reperfusion injury
- cardiovascular events
- cardiovascular disease
- oxidative stress
- type diabetes
- mitral valve
- left ventricular
- brain injury
- transcatheter aortic valve replacement