Anti-inflammatory and vasculogenic conditioning of peripheral blood mononuclear cells reinforces their therapeutic potential for radiation-injured salivary glands.

Takashi IYoshinori SumitaTakako YoshidaRyo HonmaMayumi IwatakeJorge Luis Montenegro RaudalesTomoko ShizunoShinichiro KuroshimaHaruchika MasudaMakoto SekiSimon D TranTakayuki AsaharaIzumi Asahina

Published in: Stem cell research & therapy (2019)

This effective conditioning of PBMNCs is a simple, rapid, and efficient method that provides a non-invasive source of therapeutic cells for regenerating radiation-injured atrophic SGs.

Keyphrases

anti inflammatory
induced apoptosis
cell cycle arrest
radiation induced
radiation therapy