Clinical Characteristics and Outcomes of Prolactinomas in Children and Adolescents: A Large Retrospective Cohort Study.
Yiying YangXiaoan KeLian DuanHongbo YangFeng Ying GongHui PanLinjie WangHui-Juan ZhuPublished in: The Journal of clinical endocrinology and metabolism (2024)
Pediatric prolactinomas exhibited more severe clinical characteristics in boys and in patients diagnosed during earlier stages of pubertal developments. Given the overall efficacy of PRL normalization by medication and considerable surgical remission rate in noninvasive tumors, DAs remain the first-line recommendation for prolactinomas in children and adolescents, while surgery might be viable for noninvasive tumors.
Keyphrases
- end stage renal disease
- ejection fraction
- newly diagnosed
- chronic kidney disease
- minimally invasive
- disease activity
- peritoneal dialysis
- prognostic factors
- healthcare
- early onset
- emergency department
- coronary artery disease
- skeletal muscle
- metabolic syndrome
- adipose tissue
- systemic lupus erythematosus
- patient reported
- childhood cancer