Assessing Oximetry Response to Chimeric Antigen Receptor T-cell Therapy against Glioma with 19F MRI in a Murine Model.
Fanny ChapelinBenjamin I LeachRuifeng ChenDeanne ListerKaren MesserHideho OkadaEric T AhrensPublished in: Radiology. Imaging cancer (2021)
Cell-specific Po2 measurements using perfluorocarbon probes can provide insights into effector cell function and tumor response in cellular immunotherapeutic cancer models.Keywords: Animal Studies, MR-Imaging, MR-Spectroscopy, Molecular Imaging-Cancer, Molecular Imaging-Immunotherapy Supplemental material is available for this article. © RSNA, 2021See also commentary by Bulte in this issue.
Keyphrases
- cell therapy
- papillary thyroid
- contrast enhanced
- squamous cell
- stem cells
- magnetic resonance imaging
- mesenchymal stem cells
- single molecule
- lymph node metastasis
- computed tomography
- single cell
- squamous cell carcinoma
- regulatory t cells
- childhood cancer
- young adults
- mass spectrometry
- living cells
- photodynamic therapy