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Explained variation under the additive hazards model.

Denise RavaRonghui Xu
Published in: Statistics in medicine (2020)
We study explained variation under the additive hazards regression model for right-censored data. We consider different approaches for developing such a measure, and focus on one that estimates the proportion of variation in the failure time explained by the covariates. We study the properties of the measure both analytically, and through extensive simulations. We apply the measure to a well-known survival dataset as well as the linked surveillance, epidemiology, and end results-Medicare database for prediction of mortality in early stage prostate cancer patients using high-dimensional claims codes.
Keyphrases
  • early stage
  • prostate cancer
  • public health
  • cardiovascular disease
  • molecular dynamics
  • health insurance
  • cardiovascular events
  • radiation therapy
  • electronic health record
  • neoadjuvant chemotherapy