The microbiome in prostate inflammation and prostate cancer.
Corey M PorterEva ShresthaLauren B PeifferKaren S SfanosPublished in: Prostate cancer and prostatic diseases (2018)
In health, the microbiome encourages homeostasis and helps educate the immune system. In dysbiosis, a systemic inflammatory state may be induced, predisposing remote anatomical sites to disease, including cancer. The microbiome's ability to affect systemic hormone levels may also be important, particularly in a disease such as prostate cancer that is dually affected by estrogen and androgen levels. Due to the complexity of the potential interconnectedness between prostate cancer and the microbiome, it is vital to further explore and understand the relationships that are involved.