Penicillin and cephalosporin cross-reactivity: role of side chain and synthetic cefadroxil epitopes.

Gador BogasCristobalina MayorgaÁngela Martín-SerranoRubén Fernández-SantamaríaIsabel M Jiménez-SánchezAdriana ArizaEsther BarrionuevoTeresa PosadasMaría SalasTahía Diana FernándezMaría José TorresMaría Isabel Montañez

Published in: Clinical and translational allergy (2020)

Cross-reactivity with CX in AX allergic patients is 35%, being ST not enough for prediction. R1, although critical for recognition, is not the unique factor. The synthetic determinants of CX, 1-(HOPhG-Ser-Bu) and 2-(pyrazinone) are promising tools for determining in vitro cross-reactivity to CX in AX allergic patients.

Keyphrases

end stage renal disease
ejection fraction
chronic kidney disease
newly diagnosed
peritoneal dialysis
prognostic factors
patient reported outcomes
multidrug resistant
atopic dermatitis
gram negative