Prognostic and theranostic 18F-FDG PET biomarkers for anti-PD1 immunotherapy in metastatic melanoma: association with outcome and transcriptomics.

Romain-David SebanJohn S NemerAurélien MarabelleRandy YehEric DeutschSamy AmmariAntoine Moya-PlanaFatima-Zohra MokraneRobyn D GartrellGrace FinkelLuke BarkerAmélie E BigorgneLawrence H SchwartzYvonne SaengerCaroline RobertLaurent Dercle

Published in: European journal of nuclear medicine and molecular imaging (2019)

Low tumor burden correlates with survival and objective response while hematopoietic tissue metabolism correlates inversely with survival. These biomarkers should be further evaluated for potential clinical application.

Keyphrases

pet ct
positron emission tomography
pet imaging
free survival
bone marrow
computed tomography
photodynamic therapy
single cell
risk factors
fluorescence imaging
human health
iron oxide