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The E3 ligase NEURL3 suppresses epithelial-mesenchymal transition and metastasis in nasopharyngeal carcinoma by promoting vimentin degradation.

Shi-Qing ZhouPing FengMing-Liang YeSheng-Yan HuangShi-Wei HeXun-Hua ZhuJun ChenQun ZhangYing-Qing Li
Published in: Journal of experimental & clinical cancer research : CR (2024)
Collectively, our study uncovers a novel mechanism by which NEURL3 inhibits NPC metastasis, thereby providing a promising therapeutic target for NPC treatment.
Keyphrases
  • epithelial mesenchymal transition
  • signaling pathway
  • transforming growth factor