A metal-organic framework@hydrogen-bond framework as a matrix for MALDI-TOF-MS analysis of small molecules.
Shi-Jun YinGuo-Can ZhengXin YiGuang-Ping LvFeng-Qing YangPublished in: Chemical communications (Cambridge, England) (2022)
A novel MOF@HOF composite that can serve as a matrix for analysis of small molecules by MALDI-TOF-MS was fabricated through a simple solvothermal method. Taking falvonoids as an example, this composite/matrix presents high desorption/ionization efficiency, low background interference, high salt tolerance, and satisfactory signal reproducibility for MALDI-TOF-MS analysis.