Mitochondrial respiratory chain activity is associated with severity, corticosteroid response and prognosis of alcoholic hepatitis.
Pablo Solís-MuñozMaría de la Flor-RobledoInmaculada García-RuízCarlos E Fernández-GarcíaÁgueda González-RodríguezNaina ShahRamon A BatallerMichael HeneghanCarmelo García-MonzónJosé A Solís-HerruzoPublished in: Alimentary pharmacology & therapeutics (2023)
Our results indicate that MRC activity is markedly decreased in the liver of AH patients, and, particularly, the impairment of MRC complexes I and III activity appears to have a significant impact on the clinical outcomes of patients with AH.