Histone Deacetylase 6 Regulates the Activation of M1 Macrophages by the Glycolytic Pathway During Acute Liver Failure.

Yao WangXun LiQian ChenFangzhou JiaoChunxia ShiMaohua PeiLuwen WangZuo-Jiong Gong

Published in: Journal of inflammation research (2021)

ACY-1215 could inhibit the activation of M1 macrophages by improving the glycolytic pathway through regulating DNMT1 and DDX3X/NLRP3 signals to alleviate ALF.

Keyphrases

liver failure
histone deacetylase
hepatitis b virus
dna methylation
intensive care unit
drug induced
acute respiratory distress syndrome