Single-cell analysis of chemotherapy-resistant microenvironment identifies a chemo-response biomarker for pancreatic cancer.

Ruiling XuJing ShaoJingyang LiuBo QuJing Liu

Published in: Journal of gastrointestinal oncology (2024)

The TME was closely associated with the chemotherapy response and prognosis of PDAC. Our TME-based random forest model predicted chemotherapy response with complementary knowledge to the response-related genetic mutations.

Keyphrases

locally advanced
single cell
healthcare
stem cells
genome wide
climate change
photodynamic therapy
gene expression
cancer therapy
rectal cancer
chemotherapy induced