DeepGRN: prediction of transcription factor binding site across cell-types using attention-based deep neural networks.
Chen ChenJie HouXiaowen ShiHua YangJames A BirchlerJianlin ChengPublished in: BMC bioinformatics (2021)
DeepGRN can automatically and effectively predict transcription factor binding sites from DNA sequences and DNase-Seq coverage. Furthermore, the visualization techniques we developed for the attention modules help to interpret how critical patterns from different types of input features are recognized by our model.