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Genetic variant rs1205 is associated with COVID-19 outcomes: The Strong Heart Study and Strong Heart Family Study.

Lyle G BestEsther ErdeiKarin HaackJack W KentKimberly M MalloyDeborah E NewmanMarcia O'LearyRae A O'LearyQuan SunAna Navas-AcienNora FranceschiniShelley A Cole
Published in: PloS one (2024)
A T-dominant genotype of rs1205 in the CRP gene is associated with COVID-19 death or hospitalization, even after adjustment for relevant clinical factors and potential participant relatedness. Additional study of other populations and genetic variants of this gene are warranted.
Keyphrases
  • coronavirus disease
  • sars cov
  • heart failure
  • genome wide
  • copy number
  • type diabetes
  • gene expression
  • adipose tissue
  • risk assessment
  • skeletal muscle
  • insulin resistance
  • glycemic control