Tailoring Fibroblast-Activation Protein Targeting for Theranostics: A Comparative Preclinical Evaluation of the 68 Ga- and 177 Lu-Labeled Monomeric and Dimeric Fibroblast-Activation Protein Inhibitors DOTA.SA.FAPi and DOTAGA.(SA.FAPi) 2 .

Tilman LäppchenAdrianna BilinskaEirinaios PilatisElena MenéndezSurachet ImlimthanEuy Sung MoonAli Afshar-OromiehFrank RöschAxel RomingerEleni Gourni

Published in: Molecules (Basel, Switzerland) (2024)

Dimeric compounds hold promise for therapy, while monomers are better suited for diagnostics. Finding the right combination is essential for effective disease management.

Keyphrases

pet ct
pet imaging
protein protein
amino acid
binding protein
cell therapy
big data
stem cells
computed tomography
drug delivery
bone marrow