Complete Genome Sequence of Herpes Simplex Virus 1 Strain MacIntyre.

Xiaoli JiaoHongyan SuiChristopher LyonsBao TranBrad T ShermanTomozumi Imamichi

Published in: Microbiology resource announcements (2019)

Herpes simplex virus type 1 (HSV-1) strain MacIntyre has a severe defect in the anterograde spread after replication in the nucleus. To better understand and identify the genetic determinants that lead to the unique phenotypes of the MacIntyre strain, we sequenced its genome with PacBio single-molecule real-time sequencing technology and resolved the complete sequence.

Keyphrases

herpes simplex virus
single molecule
genome wide
atomic force microscopy
living cells
single cell
early onset
copy number
gene expression