Epigenetic signatures in gastric cancer: current knowledge and future perspectives.

Fatma Sogutlu Mert Pekerbas Çigir Biray Avci

Published in: Expert review of molecular diagnostics (2022)

Epigenetic alterations take place before most genetic aberrations observed in GC and may have an initiating role in the pathogenesis of GC. They can be used as biomarkers in risk calculation, early diagnosis, and evaluation of prognosis of GC, as well as treatment targets.

Keyphrases

dna methylation
genome wide
gas chromatography
gene expression
copy number
healthcare
mass spectrometry
combination therapy
high resolution