Basement membrane proteins in various arterial beds from individuals with and without type 2 diabetes mellitus: a proteome study.
Lasse Bach SteffensenXenia Emilie Sinding IversenRasmus Søgaard HansenPia Søndergaard JensenAnne-Sofie Faarvang ThorsenJes Sanddal LindholtLars Peter Schødt RiberHans Christian BeckChristina Lund KidholmPublished in: Cardiovascular diabetology (2021)
Our results suggest that accumulation of BM proteins is a general phenomenon in the medial layer of non-atherosclerotic arteries in patients with T2DM. Moreover, we identify additional T2DM-associated effects on the arterial proteome, which requires validation in future studies.