Pedunculated mucosa-associated lymphoid tissue (MALT) lymphoma causing gastric outlet obstruction.

We report the case of an 86-year-old female presented with anemia and nausea. She underwent esophagogastroduodenoscopy that revealed a giant pedunculated polyp located in the gastric corpus protruded into the bulb causing gastric outlet obstruction. Endoscopic resection was performed. The histological evaluation confirmed the atypical presentation of a pedunculated low-grade MALT-lymphoma with immunohistochemical stain CD20 (+) in the submucosal with normal gastric mucosa (with previous biopsies showing non-specific mucosa inflammation). Endoscopic resection allowed both diagnosis and symptomatic resolution.