Association between ERα polymorphisms and systemic lupus erythematosus: susceptibility and in silico analysis.

Saeedeh SalimiAbbas Mohammadpour-GharehbaghFarshid KeshavarziFarzaneh Farajian-MashhadiMahdieh MousaviMahnaz Sandoughi

Published in: International journal of rheumatic diseases (2018)

The ESR α PvuII and XbaI polymorphisms have no association with SLE; however, the combination of the TC/AA and CC/GG genotypes were associated with SLE susceptibility.

Keyphrases

systemic lupus erythematosus
disease activity
estrogen receptor
molecular docking
rheumatoid arthritis
breast cancer cells
endoplasmic reticulum
molecular dynamics simulations