Notch activation leads to loss of myoepithelial differentiation and poor outcome in solid adenoid cystic carcinoma.

Ye ZhangXiaoxiao LiuChuan-Xiang ZhouTie-Jun Li

Published in: Oral diseases (2020)

Dysregulated Notch signalling plays a critical role in AdCC severity. Notch activation may contribute to loss of myoepithelial differentiation as well as high proliferation and metastasis rates in solid AdCC.

Keyphrases

cell proliferation
signaling pathway