The intricate relationship between obesity, type 2 diabetes and female breast cancer: A retrospective study of 335 women.
Ilaria MilaniChiara GaitaGloria GuariscoMarianna ChinucciRoberta ParisellaSilvia PiroliEleonora BrunoAnnunziata MartellucciElena De FalcoFabio RicciAntonella CalogeroFrida LeonettiDanila CapocciaPublished in: Obesity science & practice (2024)
These results confirm excess body weight and T2D as unfavorable prognostic factors in terms of the presence of the TNBC subtype, tumor metastasis, recurrence, and aggressiveness (G3 and Ki-67 > 20%). This study highlights the importance of prevention in all women, with early screening, and adequate nutritional programs.
Keyphrases
- prognostic factors
- body weight
- type diabetes
- insulin resistance
- polycystic ovary syndrome
- metabolic syndrome
- weight loss
- public health
- cardiovascular disease
- glycemic control
- breast cancer risk
- adipose tissue
- weight gain
- neoadjuvant chemotherapy
- pregnancy outcomes
- free survival
- high fat diet induced
- lymph node
- radiation therapy
- young adults