Huangqi-Honghua Combination Prevents Cerebral Infarction with Qi Deficiency and Blood Stasis Syndrome in Rats by the Autophagy Pathway.

Yue ChenLu LeiKai WangRuimin LiangYi QiaoZhijun FengJuanli ZhangMin BaiHaixia ChenJiaxin ZhaoXingzhao XiongJinyi Cao Xia Shen Zhifu Yang

Published in: Evidence-based complementary and alternative medicine : eCAM (2022)

HQ-HH protects from CI/RI, and its underlying mechanism may involve the activation of the PI3K-Akt-mTOR signaling pathway, relating to the changes in the composition of intestinal flora.

Keyphrases

signaling pathway
pi k akt
epithelial mesenchymal transition
induced apoptosis
cell death
endoplasmic reticulum stress
oxidative stress
case report
mouse model
replacement therapy