Interplay between FACT subunit SPT16 and TRIM33 can remodel chromatin at macrophage distal regulatory elements.

Federica FerriVanessa PetitVilma BarrocaPaul-Henri Romeo

Published in: Epigenetics & chromatin (2019)

Thus, sequestering of SPT16/FACT by TRIM33 at PU.1-bound distal regions might represent a new regulatory mechanism for RNA Pol II recruitment and transcription output in macrophages.

Keyphrases

transcription factor
minimally invasive
gene expression
dna damage
adipose tissue
protein kinase
oxidative stress