Pharmacodynamic Material Basis and Potential Mechanism Study of Spatholobi Caulis in Reversing Osteoporosis.

Jianpeng XiaoWei ShangZhiming ZhaoJun Jiang Jianping Chen Hui Cai Jinjin HeZhihui CaiZihan Zhao

Published in: Evidence-based complementary and alternative medicine : eCAM (2023)

SC had the hierarchical network characteristics of "multicomponents/multitargets/multifunctions/multipathways" in reversing OP, but AGE-RAGE signaling pathway may be the main regulatory mechanism.

Keyphrases

signaling pathway
epithelial mesenchymal transition
transcription factor
induced apoptosis
bone mineral density
risk assessment
cell proliferation
body composition
endoplasmic reticulum stress