Comparative Analysis of CT Texture in Lumbar and Femur and Its Correlation with Bone Mineral Density and Content over Time: An Exploratory Study.

The innovative methodology utilizing morphometric texture analysis in CT HUs offers an indirect, yet promising, approach for osteoporosis screening by providing estimations of BMC and its temporal changes. The estimations demonstrate moderate positive correlations with DXA measures, suggesting a potential alternative in circumstances where DXA scanning is limited.