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Identification of New Markers of Angiogenic Sprouting Using Transcriptomics: New Role for RND3.

Colette A AbbeyCamille L DuranZhishi ChenYanping ChenSukanya RoyAshley CoffellTimothy M SveeggenSanjukta ChakrabortyGregg B WellsJiang ChangKayla J Bayless
Published in: Arteriosclerosis, thrombosis, and vascular biology (2024)
Validation of multiple genes, including rounding 3, revealed a functional role for this gene signature early in the angiogenic process. This study expands the list of genes associated with the acquisition of a tip cell phenotype during endothelial cell sprout initiation.
Keyphrases
  • single cell
  • genome wide
  • endothelial cells
  • bioinformatics analysis
  • cell therapy
  • stem cells
  • copy number
  • bone marrow
  • transcription factor
  • mesenchymal stem cells
  • genome wide analysis