Clinical outcomes associated with orphenadrine deliberate self-poisoning: a retrospective poisons centre study.

Published in: Clinical toxicology (Philadelphia, Pa.) (2024)

Orphenadrine doses up to 10 g were associated with antimuscarinic toxicity and sedation, but not severe cardiotoxicity. More research exploring the effect of dose and formulation on outcomes is required.

Keyphrases

drug delivery
oxidative stress
early onset
mechanical ventilation
metabolic syndrome
skeletal muscle
extracorporeal membrane oxygenation